If you are sending more than 200 messages per day or need to send to mail merge list:

Gold package - customized standalone application for mass  mailing  - Customer Relationship Management (CiviCRM)

• Contacts and Groups
  • Overview of Contacts and Groups
• Mailings - easily send mailings to your contacts and members
  • Overview of CiviMail
  • Intro to HTML Editor
  • How to create a Newsletter Mailing - part one
  • How to create a Newsletter Mailing - part two

Silver package used for non-Drupal websites: for more information or to sign up for free 30 day trial go to http://www.e-listmail.com/

Bronze package - used to relay very large volume of email using your favorite desktop email application like Outlook or Mozilla Thunderbird via SMTP servers with good reputation that guarantee you better delivery rate (less bounces and spam filter hits) and no risk of getting your email account blacklisted or suspended for generating too much outgoing email traffic.